AVRA Laboratories Private Limited

Manufacturing & R&D Infrastructure



	Corey & Venkataraman Research Wings - R&D Unit 1
	Fleming & Ley Research Block - R&D Unit 2
	Pilot Plants
	Sune Bergstrom cGMP Facility
	Avra Synthesis - Unit 3
	Vizag Manufacturing Facility

Corey - Venkataraman Research Wings - R&D Unit 1

	Total Land : 2 acres
	Total Built-up area : 19,000 sq.ft.

	FACILITIES

		9 R&D labs of (5400 sq.ft. with 36 Fume Hoods )
		Class-100,00 clean room facility for kilo quantity manufacturing of APIs and intermediates (1840 sq.ft.)
		QA & QC infrastructure (2400 sq.ft.)

	PILOT PLANT

		8 Reactors of 250 L to 2000 L (Both SS and glass-lined)
		Clean rooms fitted with HEPA filters and dedicated air handling systems

Fleming & Ley Research Block - R&D Unit 2

	Total Land : 8 acres
	Total Built-up area : 30,000 sq.ft.

	FACILITIES

		20 R & D labs of 10,070 sq.ft. with 108 Fume Hoods
		QA & QC / NMR infrastructure (2380 sq.ft.)
		Hydrogenation labs ( 600 sq.ft. )

			50 Lts with 250 psi & 500 Lts with 100 psi)
			1 L - 2 L Parr H2 shakers , 1500 psi 2 L autoclaves

		Library, Conference Room, Manager’s Cabins, Stores and Admin.

	PILOT PLANT

		Built-up area of 17300 sq.ft.

			ELEVEN Reactors of from 250 Lts to 3000 Lts (both SS and glass-lined)
			SIX All glass assembly units of 100 Lts

	cGMP kilo labs: TWO Facilities

		2000 sft of Class 100,000

		5000 sft of Class 100,000

Sune Bergstrom cGMP Facility

	5000 sq.ft. with a Class - 100,000 contained unit & US FDA approvable Facility
	Full protection pressurized suits with carbon monoxide filtration systems
	The equipment includes fume-hoods,

		SS and glass-lined reactors ranging from 150 to 250 Lts
		FOUR 100 Lts all Glass Assembly set-up

Quality Assurance

	In order to ensure compliance with international standards, Avra has implemented comprehensive documentation for Standard Operating Procedures, Test Method Documentation, Limit Specification and Qualifications. The QC department is equipped with:

		300 Bruker NMR
		LCMS
		12 HPLCs (Waters and Shimadzu)
		GC, FT-IR, U V spectrometer and Polarimeters
		Flash Chromatography (Biotage)

The R&D labs are ISO 9001 certified by BVQI

	All intermediates, penultimate and final products are characterized by NMR, GC, HPLC and LCMS to ensure their purity