| Custom
Synthesis |
| Scaffolds and building blocks |
| Novel reagents |
| Chiral compounds |
| Reference compounds |
| Specialty chemicals and intermediates including
Prostaglandins, Heterocycles, β-lactams,
Carbohydrates, Boronic acids, etc |
| |
| Process
Chemistry & Manufacturing |
| Synthetic route identification, process optimization
for multi-step synthesis of chemical entities on a multi-kilo to multi-ton
scale (both under GMP or non-GMP). |
| |
| Hazardous Chemistry
|
| Lithiations, Hydrogenations, Halogenations, Nitrations
and Cyanations all done on a large scale. |
| |
| Combi-Chem Synthesis &
Medicinal Chemistry |
| |
| Oncology |
| Campthothecin / lrinotecan intermediates and analogs
|
 |
| Bicalutamide |
 |
| Steroids |
| Mifepristone |
 |
| Irinotecan and intermediates |
| |
 |
- Avra is currently producing Irinotecan and Camptothecin
derivatives with significantly higher levels of drug purity
compared to the existing product forms.
- These compounds are being made on multi-kilo scale
- Patent
# = WO2007/-015259 A2
|
|
